主讲课程

本科生：《生物工艺学》、《发酵工程》、《生工类专业论文写作》

研究生：《生物炼制技术》、《学科科技英语写作》

个人简介

信丰学，新加坡国立大学博士、教授、博士生导师，中德废弃碳资源生物炼制国际联合实验室执行主任。2008-2016年在新加坡义安理工学院和新加坡国立大学担任研究工程师和博士后职位，获国家职工基金委“国家优秀自费职工奖学金”。2016年加入999策略手机论坛网址，“入选全球前2%顶尖科学家榜单（2022年）”，获江苏省“杰出青年基金”、 “泰山产业创新领军人才”、“侯德榜化工科学技术奖”、江苏省“六大人才高峰高层次人才” 等。  

主要从事：1) 木质纤维素、厨余垃圾等废弃碳资源CBP和精细化学品合成人工混菌体系的设计、构建与功能调控；2) GRAS级安全酵母的开发和细胞工厂构建，尤其针对功能脂肪酸、胡萝卜素、虾青素等医药营养品。主持国家自然科学基金面上项目、国家重点研发“合成生物学”重点专项子课题、江苏省杰出青年基金、泰山产业领军人才、江苏省农科院自主创新项目等10余项省部级以上课题；主持中国-德国联邦教研部(BMBF)国际合作项目1项；主持企业委托合作横向项目5项，其中类胡萝卜素、虾青素、微生物油脂等已实现产业化生产，并开发了其在饲料、特产、宠物等领域的应用；成果以第一完成人获江苏省能源研究会科技进步一等奖、江苏省农学会技术创新二等奖。

迄今为止，以第一/通讯作者发表SCI论文90余篇，其中5篇被选为封面论文，发表中文论文10篇；研究成果发表在生物工程领域权威期刊Green Chemistry、Biotechnology and Bioengineering、ACS Synthetic Biology、Chemical Engineering Journal、ACS Sustainable Chemistry & Engineering、Journal of Agricultural and Food Chemistry、Biotechnology for Biofuels and Bioproducts、Trends in Biotechnology、Biotechnology Advances等。以第一发明人申请中国发明专利25件，授权10件。参编3部英文专著；主（参）编中文专著6部。

学术组织兼职：

英文期刊《BioDesign Research》副主编

SCI期刊《Biotechnology for Biofuels and Bioproducts》编委

SCI期刊《Frontiers in Bioengineering and Biotechnology》编委

SCI期刊《Frontiers in Energy Research》编委

英文期刊《Green Carbon》编委

英文期刊《Synthetic Biology and Engineering》编委

中文核心期刊《生物学杂志》编委

担任中国食品科学技术学会酶制剂分会理事、上海市生物工程学会一碳专委会委员、新加坡生物能源协会会员、中国化工学会专业会员等

荣誉获奖：

2017 江苏省“双创博士”

2018 江苏省“六大人才高峰”高层次人才

2019 江苏省“生物技术优秀青年学者”

2021 侯德榜化工科学技术奖－青年奖

2021国际遗传工程机器竞赛（iGEM）银奖指导教师

2021江苏省农学会科技奖技术创新一等奖

2022 江苏省杰出青年基金

2022江苏省能源研究会青年科技奖

2023山东省泰山产业领军人才

2023 江苏省能源研究会科技进步一等奖（排名第一）

2023 江苏省农学会技术创新二等奖（排名第一）

代表性成果

代表性科研论文：

1). Fengxue Xin*, et al. Spatial niche construction for consortium-based consolidated bioprocessing system. Green Chemistry. 2022; 24, 7941.

2). Fengxue Xin*, et al. Compartmentalization of a synergistic fungal-bacterial consortium to boost lactic acid conversion from cellulose via consolidated bioprocessing. Green Chemistry. 2023; 25, 2011-2020.

3). Fengxue Xin*, et al. Construction of a microbial consortium for the de novo synthesis of butyl butyrate from renewable resources. Journal of Agricultural and Food Chemistry. 2023 Feb 2.doi: 10.1021/acs.jafc.2c07650.

4). Fengxue Xin*, et al. Transcriptomic analysis reveals the potential mechanisms for improving carotenoid production in Rhodosporidium toruloides Z11 under light stress. Journal of Agricultural and Food Chemistry. 2023. Accepted.

5). Fengxue Xin*, et al. Increased lipid production in Yarrowia lipolytica from acetate through metabolic engineering and co-substrates fermentation. ACS Synthetic Biology. 2021; 10, 3129-3138.

6). Fengxue Xin*, et al. The de novo synthesis of 2-phenylethanol from glucose by the synthetic microbial consortium composed of engineered Escherichia coli and Meyerozyma guilliermondii. ACS Synthetic Biology. 2022; 11, 4018-4030.

7). Fengxue Xin*, et al. Consolidated bioprocessing of hemicellulose-enriched
lignocellulose to succinic acid through a microbial cocultivation system. ACS Sustainable Chemistry and Engineering. 2020; 8, 9035-9045.

8). Fengxue Xin*, et al. Design and optimization of artificial light-driven microbial consortia for the sustainable growth and biosynthesis of 2-phenylethanol. Chemical Engineering Journal. 2023; doi.org/10.1016/j.cej.2023.143050.

9). Fengxue Xin*, et al. Consolidated bioprocessing performance of a two‐species microbial consortium for butanol production from lignocellulosic biomass. Biotechnology and Bioengineering. 2020; 1-11.

10). Fengxue Xin*, et al. Metabolic engineering of Pichia pastoris for malic acid production from methanol. Biotechnology and Bioengineering. 2021; 118:357-371.

11). Fengxue Xin*, et al. Quantitative proteomic analysis to reveal expression differences for butanol production from glycerol and glucose by Clostridium sp.

strain CT7. Microbial Cell Factories. 2021; 20:12.

12). Fengxue Xin*, et al. Simultaneous fermentation of glucose and xylose to butanol by Clostridium sp. strain BOH3. Applied Environmental Microbiology. 2014; 80:15.

13). Fengxue Xin*, et al. Enhanced β-carotene production in Yarrowia lipolytica through the metabolic and fermentation engineering. Journal of Industrial Microbiology and Biotechnology. 2023. doi.org/10.1093/jimb/kuad009

14). Fengxue Xin*, et al. Comprehensive evaluation for the one-pot biosynthesis of butyl acetate by using microbial mono- and co-cultures. Biotechnology for Biofuels. 2021; 14:203.

15). Fengxue Xin, et al. Enhanced isopropanol–butanol–ethanol mixture production through manipulation of intracellular NAD(P)H level in the recombinant Clostridium acetobutylicum XY16. Biotechnology for Biofuels. 2018; 11:12.

16). Fengxue Xin*, et al. Co-production of single cell oil and gluconic acid using oleaginous Cryptococcus podzolicus DSM 27192. Biotechnology for Biofuels. 2019; 12:127.

17). Fengxue Xin*, et al. Microbial co-culturing of Chlorella sp. and Rhodotorula toruloides for the enhanced microbial lipid production. Fuel. 2022; 324:124609.

18). Fengxue Xin*, et al. Continuous self-provided fermentation for microbial lipids production from acetate by using oleaginous yeasts Cryptococcus podzolicus and Trichosporon porosum. Renewable Energy. 2020; 146:737-743.

19). Fengxue Xin*, et al. High butanol production from glycerol by using Clostridium sp. strain CT7 integrated with membrane assisted pervaporation. Bioresource Technology. 2019; 288:121530.

20). Fengxue Xin*, et al. Co‐production of lipids and carotenoids by Rhodosporidium toruloides from cane molasses through the temperature and pH shifted strategies. Biofuels Bioproducts & Biorefining. 2023; 10.1002/bbb.2477.

21). Fengxue Xin*, et al. Carotenoids production and genome analysis of a novel carotenoid producing Rhodococcus aetherivorans N1. Enzyme and Microbial Technology. 2023;164:110190.

代表性综述论文：

1). Fengxue Xin*, et al. Bioprocessing butanol into more valuable butyl butyrate. Trends in Biotechnology. 2019; 37:9.

2). Fengxue Xin*, et al. Designing synthetic microbial consortia for biofuel production. Trends in Biotechnology. 2020; 38:8.

3). Fengxue Xin*, et al. Emerging applications of 3D printing in biomanufacturing. Trends in Biotechnology. 2021; 39:11.

4). Fengxue Xin*, et al. Biotechnological potential and applications of microbial consortia. Biotechnology Advances. 2020; 40,107500.

5). Fengxue Xin*, et al. Biofilm application in the microbial biochemicals production process. Biotechnology Advances. 2021; 48:10724.

6). Fengxue Xin*, et al. Advances in the synthesis of three typical tetraterpenoids
including β-carotene, lycopene and astaxanthin. Biotechnology Advances. 2022; 61, 108033.

7). Fengxue Xin*, et al. Current status and perspectives of 2 phenylethanol production through biological processes. Critical Reviews in Biotechnology. 2019; 39(2): 235-248.

8). Fengxue Xin*, et al. Applications of synthetic microbial consortia in biological control of mycotoxins and fungi. Current Opinion in Food Science. 2023; doi.org/10.1016/j.cofs.2023.101074.

9). Fengxue Xin*, et al. Applications of synthetic light-driven microbial consortia for biochemicals production. Bioresource Technology. 2022; 351:126954.

10). 信丰学*, 等. 人工多细胞体系设计与构建研究进展. 《合成生物学》. 2020; 1(3):267-284.

11). 信丰学*, 等.   “十四五”背景下合成生物学产业发展趋势分析.《生物学杂志》. (特邀) 2023.

12). 信丰学*, 等.   微生物发酵法合成虾青素的研究进展.《合成生物学》. 2023. doi: 10.12211/2096-8280.2023-065.

主编/参编专著

英文专著：

1). Fengxue Xin, et al. Chapter 9: Biosynthetic Technology and Bioprocess Engineering (Elsevier: Current Development in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies. eBook ISBN：9780444640864; 主编：Sudhir P. Singh, Ashok Pandey, Guocheng Du and Sudesh Kumar)

2). Fengxue Xin, et al. Bioconversion of Methanol by Synthetic Methylotrophy (Springer: One-carbon Feedstocks for Sustainable Bioproduction. eBook ISBN：978-3-031-06853-9; 主编：An-Ping Zeng; Nico J. Claassens)

3) Fengxue Xin, et al. Chapter 8: Biochemical Production of Bioalcohols (Elsevier: Handbook of Biofuels Production. eBook ISBN：978-0-323-91193-1；主编：Rafael Luque; Carol Sze Ki Lin; Karen Wilson; James Clark)

中文专著：

主编《环境分子微生物学》；参编新版国家级规划教材《代谢工程与合成生物学》、《微生物与人类》、《生物质利用原理与技术》；参编专著《非粮生物质炼制技术》；参译英文经典教材《图解生物技术》。

代表性授权发明专利（5件）：

联产不饱和脂肪酸和类胡萝卜素的菌株及其应用，ZL202110345911.8，排1

变温发酵生产微生物油脂和类胡萝卜素的方法，ZL202210128191.4，排1

一株可以共利用葡萄糖和木糖的丙酮丁醇梭菌及其应用，ZL202010196517.8，排1

一种微生物混菌发酵与原位萃取相结合生产丁酸丁酯的方法，ZL202010096092.3，排1

一株高抗逆性解脂耶氏酵母及其应用，ZL201810262573.X，排1

联系地址：

江苏省南京市江北新区浦珠南路30号999策略白菜手机论坛

邮编：211816