主讲课程

《人体解剖生理学》、《药理学》、《工业药剂学》

个人简介

博士，美国普渡大学访问学者，999策略白菜手机论坛制药工程系副主任。从事药物靶向输送、药物纳米晶体、纳米药物体内命运方向的研究。负责完成1项美国FDA研究课题，主持企业横向合作项目5项，参与多项国家级、省部级纵向科研项目。曾获999策略手机论坛网址青年教师授课竞赛二等奖，入选江苏省“双创计划”科技副总。曾任Crystals杂志客座编辑，以第一作者或通讯作者在Journal of Controlled Release、ACS Applied Materials & Interfaces、International Journal of Pharmaceutics、European Journal of Pharmaceutical Science等杂志上发表学术论文20余篇，申请发明专利3项，授权发明专利1项，获江苏省科技进步三等奖1次，泰州市科技进步奖一等奖1次。

代表性成果

1. Meng Z, Fu B, Yang Z, Xu Y, Huang H, Bai Y, Fang X, Shen S, Yang J, Yong J, Tao X, Ma C, Miao W, Ren H, Wang Y, Xu H, Li X. Polydopamine-coated thalidomide nanocrystals promote DSS-induced murine colitis recovery through Macrophage M2 polarization together with the synergistic anti-inflammatory and anti-angiogenic effects. Int J Pharm. 2023; 630: 122376.

2. Meng Z^* (共同通讯), Fang X, Fu B, Qian C, Yang Z, Bai Y, Tao X, Huang H, Ma C, Miao W, Ren H, Wang A^*, Li X^*. Tumor immunotherapy boosted by R837 nanocrystals through combining chemotherapy and mild hyperthermia. J Control Release. 2022; 350: 841-856.

3. Cai C, Meng Z (共同一作), Zhao L, Wu T, Xu X, Zhu Y^*. A self-assembled peptide hydrogel for wound repair. Materials for life sciences. 2022; 57: 1345–1361.

4. Meng Z^* (共同通讯), Wang H, Fang X, Liu Z, Yang Z, Yong J, Yang Q, Bai Y, Ren H, Xu H^*, Li X^*. Surface decoration via physical interaction of cupric diethyldithiocarbamate nanocrystals and its impact on biodistribution and tumor targeting. ACS Appl Mater Interfaces. 2021; 13(31): 36894-36908.

5. Meng Z, Boyce HJ^*, Sun D, Kinjo M, Raofi S, Li T^*. Preferential oxycodone loss of physically manipulated abuse deterrent oxycodone HCl extended release tablets prepared for nasal insufflation studies. Pharm Res. 2021; 38(7): 1263-1278.

6. Xu K, Meng Z (共同一作), Mu X, Sun B, Chai Y^*. One single site clinical study: to evaluate the safety and efficacy of immunotherapy with autologous dendritic cells, cytokine-induced killer cells in primary hepatocellular carcinoma patients. Front Oncol. 2020; 10: 581270.

7. Liu K, Meng Z (共同一作), Li Y, Liu J, Xu Y, Wang Y^*, Li X^*. Preparation and evaluation of mosapride citrate dual-release dry suspension. AAPS PharmSciTech. 2019; 20(4): 155.

8. Gao W, Lee D, Meng Z, Li T^*. Exploring intracellular fate of drug nanocrystals with crystal-integrated and environment-sensitive fluorophores. J Control Release. 2017; 267: 214-222.

9. Meng Z, Meng L, Wang K, Li J, Cao X, Wu J, Hu Y. Enhanced hepatic targeting, biodistribution and antifibrotic efficacy of tanshinone IIA loaded globin nanoparticles. Eur J Pharm Sci. 2015; 73: 35-43.

10. Meng Z, Yang X, Hu D, Wang K, Zhi F, Chen X, Gong G, Wu J, Hu Y. Replacing heme with paclitaxel to prepare drug-loaded globin nanoassembles for CD163 targeting. J Pharm Sci. 2015; 104(3): 1045-55.